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KMID : 0357820080320010055
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Korean Journal of Legal Medicine
2008 Volume.32 No. 1 p.55 ~ p.60
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Statistical Interpretation in Making DNA-based Identifications of Mass Victims
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Shin Kyoung-Jin
Lee Hwan-Young
Yang Woo-Ick
Ha Eun-Ho
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Abstract
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DNA profiles have been increasingly used as the most reliable means to identify remains from war or mass disaster. To establish the identity with such a large set of victims, special care should be taken to correlate remains with correct family references while avoiding coincidental match between non-relatives. Therefore we address here relevant statistical and combinatorial issues in the DNA identification of mass victims. A simple and general formula for the likelihood ratio governing any potential kinship between two DNA profiles was presented, and for that purpose, the probabilities that a given relative and an individual share autosomal identical-bydescent alleles were calculated. In addition, a method dealing with the allele drop-out in kinship analysis and the estimation of a cold hit were discussed.
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KEYWORD
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mass victims, kinship, relatives, probability, likelihood, allele drop-out, cold hit
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